Synvisc

What You Should Know About Synvisc?

Synvisc is manufactured by Genzyme (Sanofi). It is an international business that creates medications to treat rare diseases, including but not limited to oncology, multiple sclerosis, renal, lysosomal storage, transplant, and immune diseases, as well as genetic and osteoarthritis.

What Is Synvisc, and What Are Its Ingredients?

Hyaluronic acid is naturally produced in our bodies. However, as we age, its production reduces. This reduction leads to wrinkles, which can be treated with dermal fillers available for purchase online in our aesthetic medicine shop. What’s more, this liquid is what lubricates our joints. Due to aging, increased pressure, or diseases, there’s less and less cushioning between joints and bones, which leads to pain and inflammation.

To treat these unpleasant symptoms, healthcare specialists use Synvisc® (Hylan G-F 20) to replace lost synovial fluid and restore patients’ comfort. This viscosupplement injection is a sterile, high molecular weight fluid that contains:

• Hylan-polymers (also known as Hyaluronans or Sodium Hyaluronate) that come from chicken combs (~8mg/milliliter) – Hylan A fluid (with an average molecular weight of approximately 6,000,000 daltons!) and Hylan B gel;
• Sodium chloride solution pH 7.2 ± 0.3, which is the primary component of saltwater (~8.5mg/milliliter). It strengthens the absorption and longevity of hylan polymers;
• Disodium hydrogen phosphate (~0.16mg/milliliter);
• Sodium dihydrogen phosphate hydrate (~0.04mg/milliliter).

Please note this nonpyrogenic, elastoviscous fluid doesn’t contain lidocaine. To make the process more comfortable for your patients, you can apply a topical anesthetic before injecting Synvisc directly into the patient’s knee.

Synvisc Benefits

Synvisc and Synvisc One can be injected with an 18-20 gauge (18–22G) needle by qualified specialists only. The syringes in the pack are disposable, so if you need to insert the fluid into another knee, you need to unpack a new needle to adhere to the strict antiseptic policies.

If the pack was damaged (which is not likely if you order Synvisc wholesale online at Cosmo Direct Supply), don’t use the drug. If everything is ok, preheat it to room temperature and insert intra-articularly to treat osteoarthritis in the knees, hips, ankles, and shoulders. Your patients will get:

• Prominent osteoarthritis pain and inflammation relief, which lasts up to six months;
• Well-lubricated and cushioned joints, ready for everyday life challenges;
• Shock absorber for the knee, hip, ankle, or shoulder;
• Bones that will no longer rub together, causing unbearable pain;
• Boosted overall joint health and quality of life.

Synvisc’s chemically cross-linked formula makes it more stable than other viscosupplements. Patients can even further improve Synvisc effects longevity if they combine Synvisc treatment with physical therapy and simple analgesics. To reduce the number of injections, consider using Synvisc One, which offers a single-dose treatment.

How Long Do Synvisc Results Last?

The manufacturer behind Synvisc claims that the results last up to 6 months. However, clinical data states that pain relief can last up to 12 months. It’s worth noting that the final result depends on your patients’ initial health state and the number of treatment sessions:

• For knee OA, it is recommended to have 3-2 milliliter injections;
• For the hips, ankles, and shoulders, it is recommended to start with a 1-2 milliliter injection, and continue only if the pain persists;
• The ideal maximum dosage is 6 injections within 6 months.

It is also recommended to have a maximum of 4 weeks’ breaks between treatment regimens. Observe your patient’s state carefully and adjust the dose if needed.

How Much Does Synvisc Injection Cost?

You can buy Synvisc from Cosmo Direct Supply online at a fair price, with quick delivery available for the USA. Additionally, we provide bulk discounts and a 5% discount for your first purchase. Please note that we sell aesthetic medicine products to licensed professionals and clinics only.

Product Name	Price
SYNVISC ONE 6ML	$170.80 You save
SYNVISC 2ML, 3 x 2ML	$175.51 You save

Prices may change, so be sure to check them once you proceed to the payment. Overall, your patients will need six injections of Synvisc, making the knee osteoarthritis treatment price $ 1442,1 (excluding your services cost). With Synvisc one, you can reduce the treatment cost by $1208,2 as it has more mL in the syringe and requires fewer injections. If you want to discuss additional discounts, we are happy to help! Contact us here.

Synvisc VS Monovisc VS Orthovisc

All these medications belong to the orthopedic products group and were created to treat osteoarthritis of the knees, hips, ankles, and shoulders. Furthermore, Monovisc and Othovisc use hyaluronic acid (from different sources) to restore joint fluid levels and relieve OA pain, while Synvisc contains hylan polymers.

• Monovisc and Synvisc One require only one injection;
• Orthovisc has a higher HA concentration, typically around 20 mg/mL, and is a multi-injection medication;
• Synvisc contains special hylan polymers that are derivatives of hyaluronan (sodium salt of hyaluronic acid) and consist of repeating disaccharide units of N-acetylglucosamine and sodium glucuronate.

All these solutions have shown efficacy in treating osteoarthritis. Your perfect choice of medication depends on various factors. Meanwhile, we at Cosmo Direct Supply will always be here, ready to support it with the best quality/price ratio and lighting-fast delivery right to your clinic.

Where Can I Buy Synvisc Wholesale Online?

You can buy Synvisc online at Cosmo Direct Supply and receive a noticeable discount on bulk orders. We cut out the middleman and source directly from European manufacturers to deliver authentic products at the best price on the market.

Why Buy Synvisc Online at Cosmo Direct Supply?

Synvisc is the number one among the most common medications for the treatment of knee osteoarthritis. It is an effective option that has been officially used in the USA after the FDA approval for 28 years now (application number P940015, Aug 8, 1997). Synvisc and Synvisc One provide quick relief from the pain and osteoarthritis inflammation, helping reduce the need for further surgeries.

Order Synvisc online at Cosmo Direct Supply and get:

• The best price on the market, especially for the bulk order;
• Factory-sealed package in pristine condition;
• Quick order processing and shipping across the USA and worldwide;
• Real-time shipping tracking;
• 24/7 customer support team, ready to answer all your questions.

In the USA, there are an estimated 14 million individuals with symptomatic knee osteoarthritis. The number has doubled since the mid-20th century and is expected to grow continuously. To help your patients feel better and bring them immediate relief, buy Synvisc online at Cosmo Direct Supply and enjoy fast nationwide delivery from our door to yours.

Who Are The Best Candidates for Synvisc Treatment?

Synvisc and Synvisc One are modern solutions for an ancient problem. They were created for one specific purpose – to treat osteoarthritis (OA) pain of the knee joints. You can use it on patients who haven’t felt any relief from conservative nonpharmacologic therapy (like physical therapy) and simple analgesics (like acetaminophen) or anti-inflammatory medications, and want to put off radical surgery until a later date.

With a proper regimen, a healthy lifestyle, light exercises, and our authentic Synvisc, your patients will experience almost instant pain relief, improved joint health, increased mobility, and enhanced quality of life.

Synvisc Contraindications and Side Effects

First of all, you mustn’t use the product if the patient is pregnant, lactating, or when the patient is less than 21 years old. The next important contraindicator is an allergy to hyaluronan (sodium hyaluronate), birds’ meat, or eggs. Your patient may not know if they have it or not, so proceed with any injection with caution and constant monitoring of your patient’s state. Here are several additional precautions:

• Do not disinfect the skin before injection with ammonium salts;
• Do not inject Synvisc in the knees of patients having knee joint infections, skin diseases, or infections in the area of the injection site;
• Do not enter the fluid into the synovial capsule and into vessels.

Our bodies and our needs are unique, so please, educate your patients accordingly. Like all medications, Synvisc has its side effects too. Common inconveniences your patients may face are:

• Swelling
• Stiffness
• Irritation
• Pain
• Allergy
• Inflammation
• Excessive heat
• Redness
• Itching

At the injection site. To relieve mild discomfort, you can suggest that your patients apply an ice pack to their knees. However, if severe side effects like a headache or nausea continue after 48 hours after the injection, it’s better to remove Synvisc from the joints, stop the treatment, and send your patient to a general healthcare specialist.

If the treatment went as planned, give your patient general after-care suggestions. They include avoiding exercise (especially those that put excessive pressure on the joints, like jogging) for at least 4 days after the injection. And recommend them to inform you of any changes in the mood, general well-being, and at the injection site.